Humans have the expectation to live long lives free from disease. The continuous development of new therapeutic strategies that promote the regeneration and optimal healing of tissues and organs damaged by trauma, disease, or congenital defects. The field of regenerative medicine aims to meet these demands, focusing on restoring lost, damaged, aged, or dysfunctional cells and their extracellular matrices to return function to tissues.
Redner Integral Health offers a limited and effective scope of regenerative approaches to improve ailing and “fatigued” tissues that could greatly improve both the span and quality of life.
Special importance among these are conditions where normal physiologic regeneration is limited or non-existent. For example,
Sarcopenia which is muscle loss in aging and inactivity.
Ability to regenerate the central nervous system would provide a higher quality of life to individuals paralyzed by spinal cord injury, suffering serious dysfunction from stroke, and living with degenerative diseases such as Parkinson’s, Alzheimer’s, and multiple sclerosis.
The use of chemical medical stimulants to promote healing and regeneration of new tissue has been used since 1937. Within the last decade millions of dollars have been spent on research investigating stem cell and blood platelet tissue regeneration.
Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function.
There Are Four Types of Regenerative Medicine Approaches:
Hormone Therapy, Stem Cell Therapy, Peptide Therapy and Telomere Maintenances
Our bodies function at peak efficiency during our youth when hormones are at their highest. It is at that time that our immune system is generally at its strongest; we build muscle instead of fat, injuries heal quickly, energy is plentiful.
As we age, the ability to produce and release certain hormones diminishes. An individual’s genetics, nutrition, exercise levels, stress and lifestyle all play an inextricable role in how this occurs. Clearly the aging process itself is different for each individual so any longevity plan must be tailored to meet each person’s needs and goals. This is especially true when the discussion of hormone replacement arises. Careful assessment of laboratory findings and how they relate to each individual experience of hormone change is essential in the decision making process.
Important hormones such as **insulin, cortisol, glucagon and growth hormone** are strongly influenced by **exercise, diet and stress changes.** Excess insulin and excess cortisol are the archenemies – responsible for fat accumulation, brain-aging, increased inflammatory tendency, high blood pressure, elevated blood lipids, oxidative stress and the list goes on. Growth hormone is responsible for a myriad of repair and rejuvenation tasks throughout the body and considered by some to be the closest thing to a “fountain of youth”. Levels of human growth hormone (HGH) are enhanced by the presence of certain nutrients and exercise and are diminished by elevated glucose and insulin.
Of course, when anyone speaks of hormones, the first thought in most minds is their reference to sex. And, yes, healthy hormone levels are essential for libido, performance and pleasure.
Perhaps, less generally known are hormones’ essential role in the harmonious orchestration of body and brain activity. Their decline to a fraction of what they were in our youth may set the stage for the mind-body deterioration we associate with “old age."
Our bodies produce more than 70,000 kinds of peptides, which bind to other cells and molecules and give them targeted directions. By tapping into and tweaking the body’s own biochemistry, we can direct those peptides to heal or restore damaged cells to bring the body back into balance.
Without the side effects of traditional medications, peptides redefine how we dispense medicine. They do their job and then recycle with no build-up or toxic effect on the body. Peptides not only prolong life but increase the quality of it, with an approach to anti-aging that heals and restores the body by using its own chemistry.
Stem Cell Therapy
Stem cell therapy involves isolating adult stem cells from umbilical cord tissue of healthy newborn babies, then injecting those cells back into the body for regeneration, restoration and repair of cells and tissues in specific areas. Stem cells contain very high levels of peptide growth factors, which signal the body’s cells to regenerate, grow and repair.
Dr. Redner uses stem cell therapy to treat patients with osteoarthritis, chronic fatigue, pulmonary disease and various autoimmune disorders. Stem cell therapy also offers cosmetic benefits, helping to promote more elasticity and suppleness in the skin. It enhances your mood and energy levels, reduces joint and body aches, boosts your sexual vitality and health, and improves vital cardiovascular and immune systems.
Telomeres are the protective ends of your DNA. When we are young, we have the longest telomere lengths; however, as we age, our telomeres become shorter. There are studies showing that when telomeres are shorter, there is a higher death rate from heart disease and from cancer.
Examples of Testing Within the Scope of Regenerative Medicine
+ DHEA (dehydroepiandrosterone)
sometimes referred to as the “mother of all steroids” is the most abundant steroid hormone in the human body. It is the precursor to testosterone and estrogen. DHEA is five to six times more concentrated in the brain where it protects, in particular, from the ravages of excess cortisol. Additionally, it stimulates growth hormone receptors and modulates insulin sensitivity, diabetes, and obesity; it is a potent immune booster and has benefits in memory and cognitive processes, collagen and skin integrity and may help with depression and insomnia.
This is the foundation hormone for other hormones including DHEA, progesterone, and testosterone. It is produced from cholesterol in the mitochondria (the energy powerhouse of the cell). Studies have shown that it has a potent stimulatory affect on the memory and cognitive function of brain and also helps block the effects of cortisol. Other benefits may include anti-inflammatory properties, improved mood and sleep, enhanced sense of well being.
Generally known for promoting sex drive in both men and women, this hormone plays an important role maintaining muscle skin and bone integrity. It strengthens the immune system and increases some mental functions particularly visual spatial ability.
Generally considered a female hormone; it is produced in small amounts in men. It has a positive effect on many organs throughout the body. It protects against coronary artery disease, improves lipids and raises good (HDL) cholesterol. Estrogen preserves bone density, and supports collagen formation. It has positive effects on mood, memory and concentration and some studies have shown may help stimulate the neurotransmitter acetylcholine, preventing Alzheimer’s.
Works together with estrogen in more than 300 receptor sites in the body. It is also a precursor for other hormones. Progesterone has a large number of functions and benefits on its own including promoting fat breakdown, maintaining bone, increasing energy, normalizing blood sugar, improving mood and protecting against cancer.
These hormones are vital in the regulation of metabolism and the production of other hormones. Thyroid hormone balance is crucial for health. Excess or inadequate thyroid function has detrimental effects on virtually every system. Obesity, heart disease, infertility, hair loss, mental illness, lethargy, visual disturbances, osteoporosis are just a few conditions arising from thyroid dysfunction.
Melatonin is a hormone known for its role in controlling our body’s clock. It has been suggested that it may even control the aging clock of the brain. It is a key player in our sleep/wake cycles. It is used a sleeping aid and also assists in recovery from jet lag. It is now recognized as a key element in maintaining hormonal balance. Additionally, melatonin is a potent anti-oxidant capable of scavenging free radicals working both on the inside and outside of every cell. It also stimulates the thymus gland (the key organ of the immune system) involved in the production of disease-fighting T-cells. Laboratory research has shown that decreasing melatonin accelerates aging and restoring melatonin re-establishes youthful function.
+ Human Growth Hormone (hGH)
Is the primary hormone produced by the pituitary gland and regulates all other hormones levels within the body. It has been referred to as the “fountain of youth hormone” due to its remarkable role in deterring the effects of biological aging. HGH affects almost every cell in the body. Like other hormones, it begins to decline with age losing about 14 % per decade after age 30 to levels by the age of 65 that are less than half of what anti-aging researchers consider optimal. In many people, it can be replaced naturally by a program that combines nutrient supplementation, amino acid precursors that effectively stimulate the pituitary to produce hGH, exercise (especially weight training), and a diet that keeps insulin in check. This is the natural approach we choose at our clinic. For those with whom this approach fails to achieve desired results, daily injections of recombinant DNA growth hormone,( costing $$thousands per year), may be an option they could investigate.
+ Documented benefits of Peptides therapy:
- Increased lean body mass and muscle strength
- Decreased body fat, especially in the abdomen
- Increased bone density
- Increased speed and quality of healing after injuries and surgeries,
- Improved skin thickness and diminished wrinkles
- Better energy and exercise recovery
- Improved sleep and emotional stability
- Increased immune response
- Improved sexual function
- Better lipid profiles
- Increased well-being, cognitive function and mental alertness